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Science Bloopers

Protopic Ointment (Posted: 4/21/2009)
submitted by Emily V
In tiny words at the bottom of this website there is a warning that Protopic may cause "rare cases of malignancy" when in fact use of Protopic has been linked to cancer in many individuals. It is important to read the fine print when it comes to ads!
 

Welcome to the healthcare professional Web site for Protopic Ointment. As the only topical calcineurin inhibitor (TCI) indicated for second-line therapy of moderate to severe atopic dermatitis (eczema), Protopic has helped patients achieve welcome itch relief when potions, lotions, contraptions, and other prescription medicines have not. Patients will try anything to ease the itch of eczema. Maybe it's time they gave up Itchcraft and tried Protopic.

In clinical studies, Protopic was found to provide:

·         LESS ITCHING. Eczema patients reported 5 times greater reduction in itch after treatment with Protopic than with vehicle1,2

·         SIGNIFICANT IMPROVEMENT. Significantly more patients had ≥90% improvement with Protopic treatment than with vehicle at 12 weeks (37% Protopic vs 7% vehicle)1

·         FAST RESULTS. 90% of adults treated with Protopic Ointment 0.1% showed improvement in 1 week6

·         EFFECTIVE TREATMENT. 97% of adults treated with Protopic Ointment 0.1% showed some improvement by end of treatment6

 

In tiny words at the bottom of the website:

WARNING: Long-term safety of topical calcineurin inhibitors has not been established (beyond 1 year of non-continuous use). Although a causal relationship has not been established, rare cases of malignancy (e.g., skin and lymphoma) have been reported in patients treated with topical calcineurin inhibitors, including Protopic. Therefore, continuous long-term use of topical calcineurin inhibitors, including Protopic, in any age group should be avoided and application limited to areas of involvement with atopic dermatitis. The diagnosis of atopic dermatitis should be confirmed if signs and symptoms do not improve within 6 weeks.